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My PHP web server with Nginx as reverse proxy says "upstream sent too big header while reading response header from upstream" And, here is how to fix it: 1. Edit the nginx configuration for my site, for example, /etc/nginx/sites-available/mysite $ sudo nano /etc/nginx/sites-available/mysite Modify these lines ...         location ~ \.php$ {                 include snippets/fastcgi-php.conf;                 fastcgi_pass unix:/run/php/php7.0-fpm.sock;                 fastcgi_buffer_size 128k;                 fastcgi_buffers 4 256k;                 fastcgi_busy_buffers_size 256k;         } ... 2. Restart nginx and enjoy $ sudo systemctl restart nginx

After setting up a new web root directory for my php app, all I see was: Access denied I removed this line in my server block and everything works: fastcgi_param PATH_TRANSLATED $document_root$fastcgi_path_info; Because I set cgi.fix_pathinfo to 0 in /etc/php/7.0/fpm/php.ini so it conflicts with the above setting.